Novel methine dyes

ABSTRACT

The present invention relates to novel methine dyes, methods for the preparation thereof and use thereof for dyeing plastics, especially polyamides, so as to obtain yellow to orange colourings with improved light fastness and improved thermal stability.

The present invention relates to novel methine dyes, methods for thepreparation thereof and use thereof for dyeing plastics.

BACKGROUND OF THE INVENTION

Although there are already numerous yellow dyes on the market forcolouring plastics, demand still exists for novel dyes with improvedproperties. In particular, there is a demand for known dyes improvedwith respect to their fastness. This applies in particular in the caseof the use for bulk colouration of polyamide.

The bulk colouration of synthetic polyamides presents higherrequirements of the colourants used than the bulk colouration of otherplastics. The processing temperatures of synthetic polyamides,particularly in combination with glass fibres, are considerably higherand also the chemical reactivity of molten polyamides, especially ofnylon-6.6, is substantially higher such that the heat stability of thecolourants used has to be exceptionally good. Pigments generally havehigh thermal stability. However, there are few pigments which satisfythe high requirements in the case of bulk colouration of plastics,particularly if high light resistance is also additionally required.

Pigments are known from the prior art which are suitable for colouringplastics in shades of yellow.

DE-A 3543512 A1 describes pigments based on azo lakes (Bayplast® yellowG) which may be used for colouring polyamide in shades of yellow.

EP-A 0074515 discloses pigments based on nickel azobarbituric acidcomplexes which may likewise be used to achieve yellow colouring ofpolyamide.

Furthermore, long known is the use of Pigment Yellow 192 (C.I. 507300)to achieve yellow colouration of plastic.

Although the pigments mentioned have good thermal stability, notransparent colouration of plastics can be achieved therewith. Pigmentscan also impair the mechanical properties of the polymers. The use ofsolvent dyes is known from the prior art in order to colour plastics intransparent shades of yellow. The mechanical properties of polymers aregenerally not adversely affected by dyes.

Known solvent yellow dyes are e.g. Solvent Yellow 114 (C.I. 47020) fromthe class of quinophthalone dyes, Solvent Yellow 160:1 (C.I. 55165) fromthe class of coumarin dyes and also Solvent Yellow 179(N-2-((4-cyclohexyl)phenoxy)ethyl-N-ethyl-4-(2,2-dicyanoethenyl)-3-methylaniline)and Solvent Yellow 93 (C.I. 48160), both from the class of methine dyes.

The properties of these yellow colourants known from the prior art arenot however always sufficient for current existing technicalrequirements and are in particular in need of improvement regardingtheir fastness properties, particularly their thermal stability.

Furthermore, yellow methine dyes having good light fastness are knownfrom EP-A 3 048 138, which also represent an improvement with respect totheir thermal stability compared to the prior art presented above, butare nevertheless worthy of further improvement since the performancerequirements in terms of polyamide colouration have increased stillfurther.

SUMMARY OF THE INVENTION

The present invention relates to novel methine dyes of the formula (I)

in which

R¹ is hydrogen, halogen, COOH or COOR⁸,

R² is hydrogen, halogen or alkyl,

R³ is hydrogen, halogen, COOH, COOR⁹ or CN,

R⁴ is alkyl or phenyl,

R⁵ and R⁶ are each independently alkyl,

R⁷ is hydrogen, halogen or alkyl,

R⁸ is alkyl and

R⁹ is alkyl.

In an alternative embodiment, the present invention relates to methinedyes of the formula (I), in which

R¹ is hydrogen, halogen, COOH or COOR⁸,

R² is hydrogen, halogen or alkyl,

R³ is hydrogen, halogen, COOH, COOR⁹ or CN,

R⁴ is alkyl or phenyl,

R⁵ and R⁶ are each independently alkyl,

R⁷ is hydrogen, halogen or alkyl,

R⁸ is alkyl and

R⁹ is alkyl, with the condition that R¹ and R³ are not both hydrogen.

DETAILED DESCRIPTION OF THE INVENTION

Alkyl in the definitions of R² and R⁴ to R⁹ refer for example tostraight-chain or branched C₁-C₆-alkyl, preferably straight-chain orbranched C₁-C₄-alkyl, especially methyl, ethyl, n- and isopropyl andalso n-, iso- and tert-butyl, which may in each case be optionally mono-or polysubstituted by the same or different substituents , for exampleby halogen, such as fluorine, chlorine or bromine, and also by —OH, —CN,—NH₂ or C₁-C₆-alkoxy.

Halogen in the definitions of R¹, R², R³ and R⁷ refer for example tofluorine, chlorine or bromine.

Preference is given to dyes of the formula (I),

in which

R¹ is hydrogen, fluorine, chlorine, COOH or COOR⁸,

R² is hydrogen, fluorine, chlorine, C₁-C₄-alkyl or CF₃,

R³ is hydrogen, fluorine, chlorine, COOR⁹ or CN,

R⁴ is C₁-C₄-alkyl or phenyl

R⁵and R⁶are each independently C₁-C₄-alkyl,

R⁷ is hydrogen, fluorine, chlorine, C₁-C₄-alkyl or CF₃,

R⁸ is C₁-C₄-alkyl and

R⁹ is C₁-C₄-alkyl.

In an alternative embodiment, preference is also given to dyes of theformula (I),

in which

R¹ is hydrogen, fluorine, chlorine, COOH or COOR⁸,

R² is hydrogen, fluorine, chlorine, C₁-C₄-alkyl or CF₃,

R³ is hydrogen, fluorine, chlorine, COOR⁹ or CN,

R⁴ is C₁-C₄-alkyl or phenyl

R⁵and R⁶are each independently C₁-C₄-alkyl,

R⁷ is hydrogen, fluorine, chlorine, C₁-C₄-alkyl or CF₃,

R⁸ is C₁-C₄-alkyl and

R⁹ is C₁-C₄-alkyl,

with the condition that R¹ and R³ are not both hydrogen.

Particular preference is given to dyes of the formula (I),

in which

R¹ is hydrogen, chlorine, COOH or COOCH₃,

R² is hydrogen, chlorine, methyl, ethyl, n-propyl, isopropyl or CF₃,

R³ is hydrogen, fluorine, chlorine, COOCH₃ or CN,

R⁴ is methyl or phenyl,

R⁵ and R⁶ are methyl and

R⁷ is hydrogen, chlorine, methyl, ethyl, n-propyl, isopropyl or CF₃.

Particular preference is also given to dyes of the formula (I),

in which

R¹ is hydrogen, chlorine, COOH or COOCH₃,

R² is hydrogen, chlorine, methyl, ethyl, n-propyl, isopropyl or CF₃ ,

R³ is hydrogen, fluorine, chlorine, COOCH₃ or CN,

R⁴ is methyl or phenyl,

R⁵ and R⁶ are methyl and

R⁷ is hydrogen, chlorine, methyl, ethyl, n-propyl, isopropyl or CF₃ ,with the condition that R¹ and R³ are not both hydrogen.

Very particular preference is given to dyes of the formula (I),

in which

R¹ is hydrogen, chlorine or COOCH₃,

R² is hydrogen or methyl,

R³ is hydrogen, fluorine or chlorine,

R⁴ is methyl,

R⁵ and R⁶ are methyl and

R⁷ is hydrogen, chlorine or methyl.

Very particular preference is also given to dyes of the formula (I),

in which

R¹ is hydrogen, chlorine or COOCH₃,

R² is hydrogen or methyl,

R³ is hydrogen, fluorine or chlorine,

R⁴ is methyl,

R⁵ and R⁶ are methyl and

R⁷ is hydrogen, chlorine or methyl,

with the condition that R¹ and R³ are not both hydrogen.

Dyes of the formula (I) can exist as stereoisomers. Formula (I)particularly includes the following four E and Z isomers of the formulae(Ia) to (Id):

wherein the substituents R¹ to R⁷ each have the general and preferreddefinitions specified for formula (I).

In a further alternative embodiment, the present invention relates tomethine dyes of the formula (Ia), in which the substituents R¹ to R⁷have the general and preferred definitions specified for formula (I).

Using the dyes of the formula (I) according to the invention, yellow toorange colouration of plastics, especially of polyamides, can beachieved, which are characterized by improved light fastness andimproved thermal stability compared with the known yellow dyes used forthese purposes. Moreover, the dyes according to the invention,surprisingly, also have improved colour strength compared to the knowndyes.

It is possible using the dyes according to the invention tosignificantly outperform the property profiles achieved to date of knownyellow dyes for plastic colouration. The present invention furtherrelates to the use of the dyes of the formula (I) according to theinvention for the bulk colouration of plastics. The dyes according tothe invention can be used here individually or in any desired mixturewith one another.

Bulk colouration in this case is understood to mean in particularmethods in which the dye is incorporated into the molten plasticmaterial, e.g. with the aid of an extruder, or in which the dye isalready added to the starting components for preparing the plastic, e.g.to monomers prior to polymerization.

Particularly preferred plastics are thermoplastics, for example vinylpolymers, polyesters, polyamides and also polyolefins, especiallypolyethylene and polypropylene, polycarbonates and polyamide. Veryparticular preference is given to polyamides, especially nylon-6.6, andnylon-6.

In the context of the present invention, the term polyamides is used asa designation for synthetic, industrially usable thermoplastic plasticsand thus differentiates this substance class from the chemically relatedproteins. Almost all significant polyamides are derived from primaryamines, since the repeating unit consists of the —CO—NH— functionalgroup. In addition, polyamides of secondary amines (—CO—NR—, R=organicradical) also exist. To prepare the polyamides, in particularaminocarboxylic acids, lactams and/or diamines and dicarboxylic acidsserve as monomers.

Nylon-6.6 is usually prepared from hexamethylenediamine (HMD) and adipicacid. It is formed by a polycondensation with elimination of water.

Nylon-6 is obtainable by ring-opening polymerization of c-caprolactamwith water as starter.

Suitable vinyl polymers are polystyrene, styrene-acrylonitrilecopolymers, styrene-butadiene copolymers,styrene-butadiene-acrylonitrile terpolymers, polymethacrylate andpolyvinyl chloride among others.

Suitable polyesters are, for example, polyethylene terephthalates,polycarbonates and cellulose esters.

The plastics to be coloured may be present individually or as mixtureswith one another, as plastic materials or melts.

When used for the bulk colouration of plastics, the dyes (I) accordingto the invention are preferably applied in finely divided form forapplication, wherein dispersants may be, but do not have to be, usedconcomitantly.

When used for the bulk colouration of plastics, the dyes (I) accordingto the invention can be used for example directly in the process of theplastic preparation after the polymerization is complete. In this case,at least one dye (I) according to the invention is preferably mixed indry form or ground with the plastic granules and this mixture isplasticized and homogenized for example on mixing rollers or in screws.However, the dyes (I) according to the invention may also be added tothe molten liquid material and homogeneously distributed by stirring.The material pre-coloured in this way may then be further processed asusual, e.g. by spinning to give bristles, threads etc. or by extrusionor in injection molding processes to give mouldings.

Since the dyes (I) are resistant to polymerization catalysts,particularly peroxides, it is also possible to add the dyes (I)according to the invention to the monomeric starting materials for theplastic preparation, e.g. of polymethyl methacrylate (PMMA) and then topolymerize in the presence of polymerization catalysts. For thispurpose, the dye is preferably dissolved in the monomeric components ormixed intimately with them.

The dyes of the formula (I) according to the invention for colouring theplastics mentioned, especially polyamide, are used preferably in amountsfrom 0.0001 to 1% by weight, especially 0.01 to 0.5% by weight, based onthe amount of polymer.

By adding pigments insoluble in the polymers, for example titaniumdioxide, it is possible to obtain corresponding useful coveredcolourations.

Titanium dioxide may be used in an amount from 0.01 to 10% by weight,preferably 0.1 to 5% by weight, based on the amount of polymer.

The present invention further relates to a method for the bulkcolouration of plastics, wherein at least one dye of the formula (I) ismixed in dry form or is ground with at least one plastic, preferably inthe form of granules, and this mixture is plasticized and homogenized,e.g. on mixing rollers or in screws.

However, the dyes (I) according to the invention may also be added tothe molten liquid material and homogeneously distributed by stirring. Itis likewise possible to add the dyes (I) according to the invention tothe monomeric starting components in the plastic preparation and then topolymerize.

The material pre-coloured in this way may then be further processed asusual, e.g. by spinning to give bristles, threads etc. or by extrusionor in injection molding processes to give mouldings.

By means of the method according to the invention, transparent orcovered brilliant yellow colourations with very good heat and lightresistance are obtained.

To carry out the method according to the invention, it is also possibleto use mixtures of the dyes of the formula (I) according to theinvention with other dyes and/or inorganic and/or organic pigments.

The present invention further relates to a method for preparing the dyesof the formula (I) according to the invention.

The dyes of the formula (I) according to the invention may be preparedby reacting at least one aldehyde of the formula (II)

in which

R¹, R³, R⁴, R⁵ and R⁶ have the general and preferred definitionsspecified for formula (I), with at least one benzothiazole derivative ofthe formula (III)

in which

R² and R⁷ have the general and preferred definitions specified forformula (I).

The aldehyde of the formula (II) can exist as stereoisomers. The formula(II) includes both possible E and Z forms.

The method for preparing the dyes (I) according to the invention byreacting the aldehydes of the formula (II) with the benzothiazolederivatives of the formula (Ill) may be carried out in a manner knownper se.

The method for preparing the dyes (I) according to the invention iscarried out generally at a temperature in the range from −10 to 180° C.,preferably from 0 to 100° C. and particularly preferably from 10 to 90°C.

The method for preparing the dyes (I) according to the invention iscarried out generally at a pressure from 900 to 1100 hPa, preferably atstandard pressure.

The method for preparing the dyes (I) according to the invention can becarried out in the presence of at least one solvent. Suitable solventsare those from the series of alcohols and formamides for example. Themethod for preparing the dyes (I) according to the invention ispreferably carried out in the presence of at least one alcohol from theseries of methanol, ethanol, propanol, and/or at least one formamidefrom the series of dimethylformamide and diethylformamide, particularlypreferably in the presence of methanol and/or dimethylformamide.

The method for preparing the dyes (I) according to the invention iscarried out in the presence of at least one base. Suitable bases are,for example, alkali metal hydroxides and alkali metal alkoxides.Preference is given to using lithium hydroxide, sodium hydroxide,potassium hydroxide and/or potassium tert-butoxide, particularlypreferably sodium hydroxide and/or potassium tert-butoxide.

In general, the method for preparing the dyes (I) according to theinvention is carried out such that the aldehyde (II) is firstlyinitially charged and the benzothiazole derivative (III) is added and,after reaction is complete, the compounds of the formula (I) areisolated. The isolation can be carried out by customary processes,preferably by filtration. The reaction product obtained can optionallybe worked-up by further method steps such as washing and drying.

To carry out the method, generally 0.8 to 1.5 mol of benzothiazolederivative (III) is used per mole of aldehyde (II). Preferably, 0.9 to1.1 mol of benzothiazole derivative (III) is used per mole of aldehyde(II) and particularly preferably 1 mol of benzothiazole derivative (III)is used per mole of aldehyde (II).

Benzothiazole derivatives of the formula (III) are known and can bepurchased as commercial products from Alfa Acer for example.

The aldehydes of the formula (II) are also known and can be prepared,for example, in a two-stage synthesis in a manner known to those skilledin the art. Here, in a first stage a), at least one indole derivative ofthe formula (IV)

in which

R⁵ and R⁶ have the general and preferred definitions specified forformula (I),

is reacted with at least one alkylating reagent and subsequently, in asecond stage b), the intermediate of the first stage is reacted with atleast one formylation reagent.

Reactions of the kind described in stage b) are known in the literatureunder the name of Vilsmeier reaction.

Generally, the reaction in stage a) is carried out such that the indolederivative of the general formula (IV) is initially charged and thealkylating agent is added optionally in the presence of a solvent.

The first stage a) of the reaction is carried out generally at atemperature in the range from 10 to 80° C., preferably from 20 to 70° C.and particularly preferably from 30 to 60° C.

The reaction in stage a) is carried out generally at a pressure from 900to 1100 hPa, preferably at standard pressure.

The reaction in stage a) may be carried out in the presence of at leastone solvent. Suitable solvents are those from the series of alcohols andwater for example. The reaction in stage a) is preferably carried out inthe presence of water as solvent.

In principle, all known alkylating reagents are suitable as alkylatingreagent (see e.g. B. K. Schwetlick, Organikum, VEB Deutscher Verlag derWissenschaften, Berlin, 15th edition 1977, pages 260, 253, 674), such asdimethyl sulfate, methyl iodide or diazomethane. Preference is given tothe use of dimethyl sulfate.

In general, at least one mole of alkylating reagent is used per mole ofindole derivative. Depending on the structure of the indole derivative,corresponding to the above stoichiometry, even higher molar amounts maybe used. Preferably, 0.9 to 1.1 mol, particularly preferably 1 mol ofalkylating reagent is used per mole of indole derivative (IV).

The intermediate prepared in stage a) can be isolated by customarymethods, by filtration for example. The intermediate prepared in stagea) is preferably further reacted directly without isolation in thesubsequent stage b).

In general, the reaction in stage b) is carried out in such a mannerthat the alkylated compound from the first stage a) in the form of thereaction solution obtained is initially charged and the formylationreagent is added, optionally in the presence of at least one solvent,and subsequently the aldehyde of the formula (II) thus prepared isprecipitated, optionally by the addition of a suitable amount of asuitable precipitant, and the aldehyde of the formula (II) is thenisolated by customary methods, by filtration for example.

The reaction in stage b) is carried out generally at a temperature inthe range from 10 to 80° C., preferably from 20 to 70° C. andparticularly preferably from 30 to 60° C.

The reaction in stage b) is carried out generally at a pressure from 900to 1100 hPa, preferably at standard pressure.

The reaction in stage b) may be carried out in the presence of at leastone solvent. Suitable solvents are formamides for example. Preference isgiven to dimethylformamide and diethylformamide, particular preferencebeing given to the use of dimethylformamide. When usingdimethylformamide, it is particularly preferable to use this in excesswherein the dimethylformamide then serves as formylation reagent andsolvent at the same time.

The formylation reagent used in stage b) is generally a mixture of atleast one formamide and at least one phosphoric acid chloride.

Preferred formamides are dimethylformamide, diethylformamide anddibutylformamide.

A preferred phosphoric acid chloride is phosphorus oxychloride.

The formylation reagent used is particularly preferably a mixture ofdimethylformamide and phosphorus oxychloride.

In general, at least one mole of formylation reagent, preferably 1.1 to1.5 mol and particularly preferably 1.1 to 1 mol, is used per mole ofalkylated compound from stage 1.

Suitable precipitants are, for example, alcohols such as methanol and/orethanol.

The precipitant used is preferably methanol and/or ethanol, especiallymethanol.

The indole derivatives of the formula (IV) are known to those skilled inthe art. They may be prepared in a manner known per se in a two-stagesynthesis by reacting an aniline derivative of the formula (V)

in which

R¹ has the general and preferred definition specified for formula (I),with a diazotization reagent and subsequent reaction with ring closurewith a ketone of the formula (VI)

in which

R⁵ and R⁶ have the general and preferred definition specified forformula (I).

The diazotization reaction is generally carried out by initiallycharging the aniline derivative and adding the diazotization reagent ata temperature in the range from 0 to 10° C. at standard pressure in anaqueous medium.

In principle, any suitable diazotization reagent is an option asdiazotization reagent. Preference is given to using an aqueous sodiumnitrite solution.

In general, the diazotization reagent is used in an amount of at leasttwo moles based on the aniline derivative (V).

The ring closure reaction with the ketone of the formula (VI) is carriedout in a manner known per se in a one-pot reaction by reducing thediazonium salt of the aniline derivative (V) to the hydrazone and byreacting the hydrazone with the ketone of the general formula (VI),preferably at a temperature in the range from 40 to 100° C., preferablyin aqueous solution, and subsequently by isolating and washing theindole derivative of the formula (IV) by customary methods, preferablyfiltration.

The aniline derivatives of the formula (V) and the ketones of theformula (VI) are known and can be purchased as commercial products, fromAlfa Acer or Sigma-Aldrich for example.

The invention is elucidated but not limited by the following examples,in which the parts are by weight and percentage values are percent byweight (% by weight).

EXAMPLES Example 1 Preparation of the Inventive Compound of the Formula(I)

where R¹=COOCH₃; R²=H; R³=H; R⁴, R⁵ and R⁶=CH₃ and R⁷=H

In 200 ml of methanol, 25.9 g (=0.10 mol) of aldehyde of the formula(II), where R¹=COOCH₃; R³=H; R⁴, R⁵ and R⁶=CH₃, and 17.4 g (=0.10 mol)of 2-benzothiazoleacetonitrile were introduced. Subsequently, the pH wasadjusted to around 10 with ca. 1 g of a 50% aqueous potassium hydroxidesolution and the reaction mixture was heated to a temperature of 60° C.and then stirred for ca. 6 hours. The mixture was then cooled to 25° C.and the reaction product isolated on a Nutsche filter. The filter cakewas washed with ca. 300 ml of methanol and ca. 1000 ml of water at atemperature of 90° C. The washed product was dried in a vacuum dryingcabinet at a temperature of 80° C. and a pressure of 200 mbar.

Yield: 36.6 g (corresponds to 88% of theory), melting point 244° C.

Examples 2 to 7

Preparation of inventive compounds of the formula (I) in which thesubstituents R¹ to R⁷ have the definitions listed in Table 1.

TABLE 1 Example R¹ R² R³ R⁴ R⁵ R⁶ R⁷ 2 Cl H Cl CH₃ CH₃ CH₃ H 3 Cl H HCH₃ CH₃ CH₃ H 4 H H F CH₃ CH₃ CH₃ H 5 COOCH₃ H H CH₃ CH₃ CH₃ Cl 6 COOCH₃CH₃ H CH₃ CH₃ CH₃ H 7 COOCH₃ CH₃ H CH₃ CH₃ CH₃ CH₃

The preparation and work-up of the compounds of examples 2 to 7 wereeach carried out in analogy to example 1 but with the followingdeviations:

Example 2

Instead of the aldehyde used in example 1, 27.0 g (=0.10 mol) of thealdehyde of the formula (II) were used where R¹=Cl; R³=Cl and R⁴, R⁵ andR⁶=CH₃.

Yield: 32.0 g (corresponds to 75% of theory), melting point 208° C.

Example 3

Instead of the aldehyde used in example 1, 23.6 g (=0.10 mol) of thealdehyde of the formula (II) were used where R¹=Cl; R³=H and R⁴, R⁵ andR⁶=CH₃.

Yield: 36.5 g (corresponds to 93% of theory), melting point 233° C.

Example 4

Instead of the aldehyde used in example 1, 21.9 g (=0.10 mol) of thealdehyde of the formula (II) were used where R¹ =H; R³=F and R⁴, R⁵ andR⁶=CH₃.

Yield: 28.2 g (corresponds to 75% of theory), melting point 211° C.

Example 5

Instead of the aldehyde used in example 1, 21.9 g (=0.10 mol) of thealdehyde of the formula (II) were used where R¹=COOCH₃; R³=H and R⁴, R⁵and R⁶=CH₃ and instead of 2-benzothiazoleacetonitrile used in example 1,20.9 g (=0.10 mol) of the benzothiazoleacetonitrile derivative of theformula (III) were used where R²=H and R⁷=Cl.

Yield: 35.1 g (corresponds to 78% of theory), melting point 218° C.

Example 6

Instead of the aldehyde used in example 1, 21.9 g (=0.10 mol) of thealdehyde of the formula (II) were used where R¹=COOCH₃; R³=H and R⁴, R⁵and R⁶=CH₃ and instead of 2-benzothiazoleacetonitrile used in example 1,18.8 g (=0.10 mol) of the benzothiazoleacetonitrile derivative of theformula (III) were used where R²=CH₃ and R₇=H.

Yield: 32.2 g (corresponds to 75% of theory), melting point 208° C.

Example 7

Instead of the aldehyde used in example 1, 21.9 g (=0.10 mol) of thealdehyde of the formula (II) were used where R¹=COOCH₃; R³=H and R⁴, R⁵and R⁶=CH₃ and instead of 2-benzothiazoleacetonitrile used in example 1,20.2 g (=0.10 mol) of the benzothiazoleacetonitrile derivative of theformula (III) were used where R²=CH₃ and R₇=CH₃.

Yield: 35.9 g (corresponds to 81% of theory), melting point 213° C.

Preparation of the Precursors Example 8 Preparation of an Aldehyde ofthe Formula (II)

where R¹=COOCH₃; R³=H and R⁴, R⁵ and R⁶=CH₃

a) diazotization

139.9 g of p-aminobenzoic acid were introduced to 270 g of 30%hydrochloric acid and the mixture was cooled to 0° C. by externallycooling. Subsequently, 174 g of a 40% aqueous solution of sodium nitritewere added. The mixture was stirred for 30 minutes and then the excessnitrite was removed with ca. 0.5 g of amidosulfonic acid.

b) Preparation of the Hydrazone and Ring Closure

A mixture of 250 g of water and 660 g of sodium hydrogensulfite, in theform of a 39% aqueous solution, was adjusted to a pH of 6.5 with 80 g ofa 40% aqueous sodium hydroxide solution. Over the course of ca. 30minutes, the diazotization solution prepared in stage a) was added,while maintaining a pH of ca. 6.5 by addition of 100 g of a 40% aqueoussodium hydroxide solution. Subsequently, the reaction mixture wasstirred at a temperature of 40° C. for ca. 1 hour. Subsequently, 560 gof 96% sulfuric acid and then 86.1 g of methyl isopropyl ketone wereadded dropwise. The reaction mixture was heated to 70° C. and stirredfor ca. 4 hours. The reaction mixture was subsequently heated to 80° C.and then stirred again for ca. 4 hours. The reaction mixture was thencooled to 25° C. and the pH was adjusted to 6.5 with ca. 800 g of a 40%aqueous sodium hydroxide solution. The reaction mixture was stirred for30 minutes and the reaction product was then isolated on a Nutschefilter and washed with 2 litres of water.

c) Preparation of the Aldehyde

The moist press cake of the ring-closed product from stage b) wasintroduced into 1200 g of water. The pH was then adjusted to 10 with ca.70 g of a 40% aqueous sodium hydroxide solution. Over the course of 1hour, 325 g of dimethyl sulfate were added dropwise maintaining a pHhere of ca. 8.5 by addition of 200 g of a 40% aqueous sodium hydroxidesolution. The reaction mixture was heated to 40° C. and stirred for ca.5 hours. The reaction mixture was subsequently heated to 60° C. and thenstirred for a further 1 hour. The reaction mixture was then left tostand whereupon a phase separation took place within 1 hour. The aqueousphase was then removed. Residual water was removed from the organicphase under reduced pressure at 80° C. and 20 mbar. 310 g ofdimethylformamide were then added dropwise to the organic phase.Subsequently, 263 g of phosphorus oxychloride were added at 40° C. overthe course of 3 hours and the reaction mixture was stirred for 5 hours.The mixture was then cooled to 20° C. and 160 g of methanol were added.The pH was then adjusted to 11 with ca. 200 g of a 40% aqueous sodiumhydroxide solution. The reaction mixture was subsequently stirred for 60minutes and then the reaction product was isolated on a Nutsche filterand washed with 160 g of methanol and 2000 g of water. The washedproduct was dried in a vacuum drying cabinet at a temperature of 80° C.and a pressure of 200 mbar.

Yield: 176.3 g (corresponds to 68% of theory)

Examples 9 to 11

Preparation of aldehydes of the formula (II) in which the substituentsR¹ and R³ to R⁶ have the definitions listed in Table 2.

TABLE 2 Example R¹ R³ R⁴ R⁵ R⁶ 9 Cl H CH₃ CH₃ CH₃ 10 F H CH₃ CH₃ CH₃ 11Cl Cl CH₃ CH₃ CH₃

Example 9 a) Diazotization

The preparation of the diazotization was carried out as specified inexample 8 a), but 268 g of 30% hydrochloric acid and 127.6 g of4-chloroaniline were used instead of 270 g of 30% hydrochloric acid and139.9 g of p-aminobenzoic acid.

b) preparation of the Hydrazone

The preparation of the hydrazone and the ring closure were carried outin analogy to example 8 b), but the diazotization solution from step 9a) was used.

c) Preparation of the Aldehyde

The moist press cake of the ring-closed product from stage b) wasintroduced into 1200 g of water. The pH was then adjusted to 10 with ca.5 g of a 40% aqueous sodium hydroxide solution. Over the course of 1hour, 153 g of dimethyl sulfate were added dropwise maintaining a pHhere of ca. 8.5 by addition of 90 g of a 40% aqueous sodium hydroxidesolution. The reaction mixture was heated to 40° C. and stirred for ca.5 hours. The reaction mixture was subsequently heated to 60° C. and thenstirred for a further 1 hour. The reaction mixture was then left tostand whereupon a phase separation took place within 1 hour. The aqueousphase was then removed. Residual water was removed from the organicphase under reduced pressure at 80° C. and 20 mbar. 275 g ofdimethylformamide were then added dropwise to the organic phase.Subsequently, 116 g of phosphorus oxychloride were added at 40° C. overthe course of 3 hours and the reaction mixture was stirred for 5 hours.The mixture was then cooled to 20° C. and 160 g of methanol were added.The pH was then adjusted to 11 with ca. 180 g of a 40% aqueous sodiumhydroxide solution. The reaction mixture was subsequently stirred for 60minutes and then the reaction product was isolated on a Nutsche filterand washed with 160 g of methanol and 2000 g of water. The washedproduct was dried in a vacuum drying cabinet at a temperature of 80° C.and a pressure of 200 mbar.

Yield: 141.4 g (corresponds to 60% of theory)

Example 10 a) Diazotization

The preparation of the diazotization was carried out as specified inexample 8 a). However, 375 g of 30% hydrochloric acid and 155.5 g of3-fluoroaniline were used instead of 270 g of 30% hydrochloric acid and139.9 g of p-aminobenzoic acid.

b) Preparation of the Hydrazone and Ring Closure

A mixture of 250 g of water and 918 g of sodium hydrogensulfite, in theform of a 39% aqueous solution, was adjusted to a pH of 6.5 with 120 gof a 40% aqueous sodium hydroxide solution. Over the course of ca. 30minutes, the diazotization solution prepared in stage a) was added,while maintaining a pH of ca. 6.5 by addition of 140 g of a 40% aqueoussodium hydroxide solution. Subsequently, the reaction mixture wasstirred at a temperature of 40° C. for ca. 1 hour. Subsequently, 776 gof 96% sulfuric acid and then 120.4 g of methyl isopropyl ketone wereadded dropwise. The reaction mixture was heated to 70° C. and stirredfor ca. 4 hours. The reaction mixture was subsequently heated to 80° C.and then stirred again for ca. 4 hours. The reaction mixture was thencooled to 25° C. and the pH was adjusted to 6.5 with ca. 1150 g of a 40%aqueous sodium hydroxide solution. The reaction mixture was stirred for30 minutes and the reaction product was then isolated on a Nutschefilter and washed with 2 litres of water.

c) Preparation of the Aldehyde

The moist press cake of the ring-closed product from stage b) wasintroduced into 1200 g of water. The pH was then adjusted to 10 with 10g of a 40% aqueous sodium hydroxide solution. Over the course of 1 hour,194 g of dimethyl sulfate were added dropwise maintaining a pH here ofca. 8.5 by addition of 120 g of a 40% aqueous sodium hydroxide solution.The reaction mixture was heated to 40° C. and stirred for ca. 5 hours.The reaction mixture was subsequently heated to 60° C. and then stirredfor a further 1 hour. The reaction mixture was then left to standwhereupon a phase separation took place within 1 hour. The aqueous phasewas then removed. Residual water was removed from the organic phaseunder reduced pressure at 80° C. and 20 mbar. 350 g of dimethylformamidewere then added dropwise to the organic phase. Subsequently, 147 g ofphosphorus oxychloride were added at 40° C. over the course of 3 hoursand the reaction mixture was stirred for 5 hours. The mixture was thencooled to 20° C. and 160 g of methanol were added. The pH was thenadjusted to 11 with ca. 200 g of a 40% aqueous sodium hydroxidesolution. The reaction mixture was subsequently stirred for 60 minutesand then the reaction product was isolated on a Nutsche filter andwashed with 160 g of methanol and 2000 g of water. The washed productwas dried in a vacuum drying cabinet at a temperature of 80° C. and apressure of 200 mbar.

Yield: 169.1 g (corresponds to 55% of theory)

Example 11 a) Diazotization

The preparation of the diazotization was carried out as specified inexample 8 a). However, 375 g of 30% hydrochloric acid and 162.0 g of3,4-dichloroaniline were used instead of 270 g of 30% hydrochloric acidand 139.9 g of p-aminobenzoic acid.

b) Preparation of the Hydrazone and Ring Closure

The preparation of the hydrazone and the ring closure were carried outin analogy to example 10 b), but the diazotization solution from step 11a) was used.

c) Preparation of the Aldehyde

The preparation and work-up of the aldehyde was carried out as specifiedin example 10 c), but the water-moist press cake of the ring-closedproduct from stage 11 b) was used.

Yield: 197.2 g (corresponds to 73% of theory)

Example 12 Preparation of a Benzothiazole Derivative of the Formula(III)

where R²=H and R⁷=H

125.2 g of 2-aminothiophenol were introduced into 260 ml of water. 22 mlof acetic acid were then added dropwise. The reaction mixture is thenheated to 35° C. Over the course of ca. 30 minutes, 69.4 g ofmalononitrile were added dropwise and the mixture was then stirred for 1hour. Subsequently, 50 ml of 30% hydrochloric acid were added dropwise.The reaction mixture was then cooled to 25° C. and the product wasisolated by means of a laboratory Nutsche filter.

Yield: 129 g dry form 74% of theory

Examples 13 to 15

Preparation of benzothiazole derivatives of the formula (III) in whichthe substituents R² and R⁷ have the definitions listed in Table 3.

TABLE 3 Example R² R⁷ 13 H Cl 14 CH₃ H 15 CH₃ CH₃

The preparation and work-up of the compounds of examples 13 to 15 wereeach carried out in analogy to example 12 but with the followingdeviations:

Example 13

159.6 g of 2-amino-5-chlorothiophenol were used instead of 125.2 g of2-aminothiophenol.

Yield: 110 g dry form 69% of theory

Example 14

139.2 g of 2-amino-5-methylthiophenol were used instead of 125.2 g of2-aminothiophenol.

Yield: 106 g dry form 76% of theory

Example 15

153.2 g of 2-amino-4,5-dimethylthiophenol were used instead of 125.2 gof 2-aminothiophenol.

Yield: 80 g dry form 52% of theory

List of Substances Purchased

Molecular Name weight Cas. No. Content Manufacturer p-Aminobenzoic acid137.2 150-13-0 98 Sigma-Aldrich Methyl isopropyl 86.1 563-80-4 99Sigma-Aldrich ketone Isopropyl methyl ketone 4-Chloroaniline 127.6106-47-8 98 Sigma-Aldrich 3-Fluoroaniline 111.1 372-19-0 99 Alfa Acer3,4-Dichloroaniline 162.0 95-76-1 99 Alfa Acer 2-Aminothiophenol 125.2137-07-5 99 Sigma-Aldrich Malononitrile 66.1 109-77-3 99 Sigma-Aldrich2-Amino-5- 159.6 23477-98-9 99 Sigma-Aldrich chlorothiophenol 2-Amino-4-139.2 23451-96-9 98 MolBase methylthiophenol 2-Amino-4,5- 153.2100601-29-4 96 Abichem dimethylthiophenol

The results of the UV/VIS measurements and absorption values for theinventive compounds of Examples 1 to 7 are listed in Table 4.

TABLE 4 Absorption maximum Inventive UV/VIS E 1/1 compound spectrum¹⁾value²⁾ Example 1 464 nm 1562 Example 2 461 nm 1212 Example 3 463 nm1491 Example 4 460 nm 1531 Example 5 464 nm 1543 Example 6 461 nm 1324Example 7 458 nm 1298 ¹⁾The UV/VIS absorption spectra of the inventivecompounds were all measured in the solvent 1-methoxy-2-propyl acetate(CAS No. 108-65-6). ²⁾The E1/1 value specified is a hypotheticalabsorption value. Initially measured is the absorbance of a solution ofthe respective sample in 1-methoxy-2-propyl acetate in a cuvette of 1 cmpath length, wherein the concentration of the solution is selected suchthat the absorption value observed at the absorption maximum is about 1.The value determined is then converted to a concentration of 1 percentby weight whereby the E1/1 value is obtained.

Practical Results A) Description of the “Thermal Stability” Test Method

In a tumbling mixer, 2 g each of the dye to be tested were mixed with1998 g of a PA6 granulate of the Durethan B30S type (commercial productfrom Lanxess Deutschland GmbH) with 1% TiO₂ which had been dried at 80°C. for 4 hours. This mixture was extruded at a material temperature ofat most 240° C. in a single-screw extruder (Stork, 25 mm screw), cooledwith water, granulated using a granulator from Sheer and dried at 80° C.for 8 hours. The heat stability of the resulting plastic granules wastested according to DIN EN 12877-2 (“Determination of colour stabilityto heat during processing of colouring materials in plastics”) (methodA) on an injection moulding machine. A sample as standard was preparedat 240° C. with a residence time in the screw of 2.5 minutes. Comparedto this standard sample, the samples to be determined were evaluatedcolouristically, which were prepared at a residence time of 5 minutesand temperatures of 240-320° C. Samples with an overall colourdifference (calculated in accordance with EN ISO 11664-4) of dE 3.0 wereevaluated as stable at the applied temperature.

The results of the thermal stability determination of the inventivecompounds of Examples 1 to 7 and also the non-inventive comparativecompounds of the prior art are listed in Tables 5 and 6.

TABLE 5 Inventive Heat stable compound to (° C.) Example 1 340 Example 2335 Example 3 340 Example 4 345 Example 5 330 Example 6 335 Example 7340

TABLE 6 Non-inventive Heat stable compound to (° C.) D.Y 201 (MacrolexDecolourization Yellow 6G) at 240° C. S. Y. 93 (Macrolex DecolourizationYellow 3G) at 240° C. S.Y 114 (Macrolex Yellow G) 240° C. S.Y 160:1(Macrolex Fluor. <240° C. Yellow 10GN) (DE 3.6 at 240° C.) Example 8 ofEP-A 3 048 138 320° C. Example 9 of EP-A 3 048 138 320° C.

What is claimed is:
 1. A dye of the formula (I)

wherein R¹ is hydrogen, halogen, COOH or COOR⁸, R² is hydrogen, halogen or alkyl, R³ is hydrogen, halogen, COOH, COOR⁹ or CN, R⁴ is alkyl or phenyl, R⁵ and R⁶ are each independently alkyl, R⁷ is hydrogen, halogen or alkyl, R⁸ is alkyl, and R⁹ is alkyl.
 2. The dye of claim 1, wherein in formula (I) R¹ is hydrogen, fluorine, chlorine, COOH or COOR⁸, R² is hydrogen, fluorine, chlorine, C₁-C₄-alkyl or CF₃, R³ is hydrogen, fluorine, chlorine, COOR⁹ or CN, R⁴ is C₁-C₄-alkyl or phenyl R⁵ and R⁶ are each independently C₁-C₄-alkyl, R⁷ is hydrogen, fluorine, chlorine, C₁-C₄-alkyl or CF₃, R⁸ is C₁-C₄-alkyl, and R⁹ is C₁-C₄-alkyl.
 3. The dye of claim 1, wherein in formula (I) R¹ is hydrogen, chlorine, COOH or COOCH₃, R² is hydrogen, chlorine, methyl, ethyl, n-propyl, isopropyl or CF₃, R³ is hydrogen, fluorine, chlorine, COOCH₃ or CN, R⁴ is methyl or phenyl, R⁵ and R⁶ are methyl, and R⁷ is hydrogen, chlorine, methyl, ethyl, n-propyl, isopropyl or CF₃,
 4. The dye of claim 1, wherein in formula (I) R¹ is hydrogen, chlorine or COOCH₃, R² is hydrogen or methyl, R³ is hydrogen, fluorine or chlorine, R⁴ is methyl, R⁵ and R⁶ are methyl and R⁷ is hydrogen, chlorine or methyl.
 5. A method for the bulk colouration of plastic, the method comprising adding one or more dyes of claim 1 into plastic as colorants for the plastic.
 6. The method of claim 5, wherein the plastic is one or more plastics selected from the group consisting of vinyl polymers, polyesters, polyolefins, polycarbonates, and polyamides.
 7. The method of claim 5, wherein the plastics are nylon-6 and/or nylon-6.6.
 8. The method of claim 5, wherein the method comprises adding to the plastic, an amount of 0.0001 to 1 percent by weight of the dyes, based on the amount of plastic.
 9. The method of claim 5, wherein the method comprises adding to the plastic, an amount of 0.01 to 0.5 percent by weight of the dyes, based on the amount of plastic.
 10. A method for the bulk colouration of plastic, the method comprising mixing the one or more dyes of claim 1 in dry form with one or more plastics, or, grinding the one or more dyes in dry form with one or more plastics, to produce a mixture, and melting and homogenizing the mixture.
 11. The method of claim 10, wherein the one or more plastics are in the form of granules.
 12. A method for the bulk colouration of plastics, the method comprising adding the one or more dyes of claim 1 to a molten plastic material comprising one or more plastics to form a mixture, and then homogenizing the mixture.
 13. A method for the bulk colouration of plastics, the method comprising mixing the one or more dyes of claim 1 with monomeric starting components for producing one or more plastics, and subsequently polymerizing the monomeric components.
 14. A method for the bulk colouration of polymethyl methacrylate (PMMA), the method comprising mixing the one or more dyes of claim 1 with one or more methyl methacrylate monomers to form a mixture, or dissolving the one or more dyes therein to form a solution, and polymerizing the monomers in the mixture or solution in the presence of one or more polymerization catalysts.
 15. A plastic composition comprising the one or more dyes of claim
 1. 16. The plastic composition of claim 15, wherein the plastic composition is a polyamide composition or a polymethyl methacrylate.
 17. A moulding comprising one or more plastic compositions of claim
 15. 18. A method for producing a dye of claim 1, the method comprising contacting one or more aldehydes of the formula (II)

in which R¹, R³, R⁴, R⁵ and R⁶ have the definitions specified in claim 1, with one or more benzothiazole derivatives of the formula (III)

in which R² and R⁷ have the definitions specified in claim
 1. 